Medique® Medi-Seltzer®

Compare active ingredient to Alka-Seltzer®



Medique® brand OTC's are the only brand available that reward you for purchasing. Learn more about our MediBucks Rebate Program here.

Medi-First® Brand


Product Information

Effervescent pain reliever and antacid with specially buffered aspirin

  • Unit dose, tamper-evident foil packets

Each tablet contains:
Aspirin 325 mg
Citric Acid 1000 mg
Sodium Bicarbonate (heat treated) 1916 mg


Available in the following package sizes:
*72 (36 x 2's) - Item 13524
36 (18 x 2's) - Item 13520
*MediBucks Point Value = 15



Drug Facts Information


Active ingredient (in each tablet): Aspirin (NSAID*) 325 mg
Purpose: Pain reliever/fever reducer
*nonsteroidal anti-inflammatory drug

Active ingredient (in each tablet): Citric Acid 1000 mg
Purpose: Antacid

Active ingredient (in each tablet): Sodium bicarbonate (heat-treated) 1916 mg
Purpose: Antacid

Inactive ingredients


For the temporary relief of
heartburn, acid indigestion, and sour stomach when accompanied with headache or body aches and pains
upset stomach with headache from overindulgence in food or drink
headache, body aches, and pain alone


Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness.

Allergy alert: Aspirin may cause a severe allergic reaction which may include:
facial swelling
asthma (wheezing)
If an allergic reaction occurs, stop use and seek medical help right away.

Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you:
are age 60 or older
have had stomach ulcers or bleeding problems
take a blood thinning (anticoagulant) or steroid drug
take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others)
have 3 or more alcohol drinks every day while using this product
take more or for a longer time than directed

Do not use
if you have ever had an allergic reaction to any other pain reliever/ fever reducer
if you are taking prescription drugs for gout, diabetes or arthritis

Ask a doctor before use if
stomach bleeding warning applies to you
you have a history of stomach problems such as heartburn
you have high blood pressure, heart disease, liver cirrhosis, or kidney disease
you are taking a diuretic
you reached age 60 or older
you are on a sodium restricted diet

Ask a doctor or pharmacist before use if you are
taking any other drugs (prescription or non-prescription). Antacids may interact with certain drugs.
under a doctor’s care for any serious condition

When using this product do not exceed recommended dosage.

Stop use and ask a doctor if
you experience any of the following signs of stomach bleeding:
      feel faint
      vomit blood
      have bloody or black stools
      have stomach pain that does not get better
pain gets worse or lasts more than 10 days
fever gets worse or lasts more than 3 days
ringing in the ears or loss of hearing occurs
redness or swelling is present in the painful area
any new symptoms appear

If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.


■ do not exceed recommended dosage
to avoid serious injury; completely dissolve tablets in 4 oz. of water before taking

Adults and children 12 to 60 years of age: 2 tablets every 4 hours. Do not exceed 8 tablets in 24 hours or do not use the maximum dosage for more than 10 days.

Children under 12 years: Do not give to children under 12 years of age.

60 years and older: Do not exceed 4 tablets in 24 hours or do not use the maximum dosage for more than 10 days.

Other Information

each tablet contains: Sodium 524 mg
read all product information before using
store at room temperature 59º-86º F (15º-30º C)
avoid excessive heat and humidity
tamper-evident sealed packets
do not use any opened or torn packet


Questions? Please contact us at 1-800-634-7680

Medique Products takes great care to ensure that the product you take is completely safe. This website contains current product information as of 7/31/20 and may differ from the information on the product packaging you may have.


Alka-Seltzer® is a registered trademark of Bayer Consumer.