Medique® Diphen

Compare active ingredient to Benadryl®



Medique® brand OTC's are the only brand available that reward you for purchasing. Learn more about our MediBucks Rebate Program here.

Medi-First® Brand


Product Information

For relief from sneezing, itchy nose and throat, and watery eyes caused by hay fever and other symptoms of allergic reactions. May cause drowsiness.

  • Unit dose, tamper-evident dual layer foil packets
  • English and Spanish labeling where possible

Each tablet contains:
Diphenhydramine HCl 25 mg


Available in the following package sizes:
*200 (200 x 1's) - Item 18447
24 (24 x 1's) - Item 18464
*MediBucks Point Value = 15



Drug Facts Information


Active ingredient (in each tablet): Diphenhydramine HCl 25 mg
Purpose: Antihistamine

Inactive ingredients*
carnauba wax*, colloidal silicon dioxide, croscarmellose sodium, D&C red #27, dicalcium phosphate*, hypromellose, lactose*, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate*, titanium dioxide

* may contain


Temporarily relieves these symptoms due to hay fever or other respiratory allergies
runny nose
itching nose or throat
itchy - watery eyes

Temporarily relieves these symptoms due to the common cold
■ runny nose
■ sneezing


Do not use
to make a child sleepy
with any other product containing diphenhydramine, even one that is used on skin

Ask a doctor before use if you have
a breathing problem such as emphysema or chronic bronchitis
difficulty in urination due to enlargement of the prostate gland

Ask a doctor or pharmacist before use if you are
taking sedatives or tranquilizers

When using this product
marked drowsiness may occur
avoid alcohol beverages
alcohol, sedatives and tranquilizers may increase the drowsiness effect
use caution when driving a motor vehicle or operating machinery
excitability may occur, especially in children

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children. In case of overdose, contact a physician or Poison Control Center immediately.


■ do not use more than directed

Adults and children: (12 years and older) Take 1 to 2 caplets every 4 to 6 hours as needed. Do not take more than 12 caplets in 24 hours, or as directed by a doctor.

Children under 12 years: Do not give to children under 12 years of age.

Other Information

each caplet may contain: calcium 25 mg
protect from light
use by expiration date on packet
store at room temperature 59º-86ºF (15º-30ºC)
tamper-evident sealed packets
do not use any opened or torn packets


Questions? Please contact us at 1-800-634-7680

Medique Products takes great care to ensure that the product you take is completely safe. This website contains current product information as of 7/31/20 and may differ from the information on the product packaging you may have.


Benadryl® is a registered trademark of McNeil Consumer Healthcare.