Medique® Pain-Off®

Active ingredient (in each tablet): Acetaminophen 250 mg
Purpose: Pain reliever/fever reducer

Active ingredient (in each tablet): Aspirin (NSAID*) 250 mg
Purpose: Pain reliever/fever reducer
*nonsteroidal anti-inflammatory drug

Active ingredient (in each tablet): Caffeine 65 mg
Purpose: Pain reliever aid

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Inactive ingredients
hypromellose, maltodextrin, microcrystalline cellulose, polyethylene glycol, povidone, sodium starch glycolate, starch, stearic acid, titanium dioxide

For the temporary relief of minor aches and pains associated with
■ headache
■ muscular aches
■ minor arthritis pain
■ back pain
■ common cold
■ toothache
■ menstrual cramps
Temporarily reduces fever.

Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness.

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Allergy alert: Aspirin (NSAIDs) may cause a severe allergic reaction which may include:
■ hives
■ facial swelling
■ asthma (wheezing)
■ shock

Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
■ skin reddening
■ blisters
■ rash

If a skin or allergic reaction occurs, stop use and seek medical help right away.

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Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take:
■ more than 4,000 mg of acetaminophen in 24 hours
■ with other drugs containing acetaminophen
■ 3 or more alcoholic drinks every day while using this product

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Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you:
■ are age 60 or older
■ have had stomach ulcers or bleeding problems
■ take a blood thinning (anticoagulant) or steroid drug
■ take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others)
■ have 3 or more alcoholic drinks every day while using this product
■ take more or for a longer time than directed

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Caffeine Warning: The recommended dose of this product contains about as much caffeine as a cup of coffee. Limit the use of caffeine-containing medications, foods, or beverages while taking this product because too much caffeine may cause nervousness, irritability, sleeplessness, and, occasionally, rapid heart beat.

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Do not use
■ with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
■ for more than 10 days for pain unless directed by a doctor
■ for more than 3 days for fever unless directed by a doctor
■ if you ever have had an allergic reaction to any other pain relievers/ fever reducers
■ right before or after heart surgery
■ if you are taking prescription drugs for gout, diabetes, or arthritis

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Ask a doctor before use if
■ stomach bleeding warning applies to you
■ you have high blood pressure, heart disease, liver cirrhosis, or kidney disease
■ you are taking a diuretic
■ you have a history of stomach problems such as heartburn
■ you have asthma

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Ask a doctor or pharmacist before use if you are
■ taking the blood thinning drug warfarin
■ under a doctor’s care for any serious condition
■ taking any other drug

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When using this product
■ take with food or milk if stomach upset occurs

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Stop use and ask a doctor if
■ you experience any of the following signs of stomach bleeding:
      ■ feel faint
      ■ vomit blood
      ■ have bloody or black stools
      ■ have stomach pain that does not get better
■ symptoms do not improve
■ pain gets worse or lasts more than 10 days
■ fever gets worse or lasts more than 3 days
■ ringing in the ears or loss of hearing occurs
■ redness or swelling is present in the painful area
■ any new symptoms appear

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If pregnant or breast-feeding, ask a health care professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

■ do not take more than directed

Adults and children: (12 years and older) Take 2 tablets with water every 6 hours as needed. Do not take more than 8 tablets in 24 hours.

Children under 12 years: Do not give to children under 12 years of age.

■ read all product information before using
■ store at room temperature 59º-86ºF (15º-30ºC)
■ avoid excessive heat and humidity
■ tamper-evident sealed packets
■ do not use any opened or torn packets